Artemisinin resistance—the clock is ticking

Nicholas White | 17 Dec 2023
The Lancet
Artemisinin resistance in falciparum malaria has emerged in western Cambodia. 1 Chloroquine resistance arose in exactly the same place 50 years ago, spread to Africa, and killed millions of children. 2—4 Resistance to sulfadoxine-pyrimethamine (the antimalarial combination that followed chloroquine) in Africa can be traced to the same origin. 5 The parallels are chilling. If artemisinin resistance spreads widely, it will derail current initiatives to control and eliminate malaria. The consequences will be disastrous.

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