In early 2013 a batch of falsified Coartem was discovered in Yaoundé, Cameroon, containing no active pharmaceutical ingredients. Coartem is a fixed dose Artemesinin based combination therapy (ACT) (Artemether 20mg and Lumefantrine 120mg), used for the treatment of Plasmodium falciparum malaria.
The genuine product is manufactured by Novartis and is a WHO pre-qualified medicine. A pharmacist in Yaoundé requested Minilab testing as he suspected that the product was ineffective. The product failed screening by the minilab and was forwarded by an NGO to a WHO pre-qualified laboratory in Nairobi, Kenya, for more detailed analysis. Subsequent testing revealed that the product contained neither of the correct active pharmaceutical ingredients.
On 9 April 2013 WHO were informed by the NGO of the discovery of this falsified batch. Contact was subsequently established with all National Medicine Regulatory Authorities and Novartis.It has now been established that a second batch of falsified Coartem has been circulating in West and Central Africa recently. more »
Mosquitoes carrying the malaria parasite are more attracted to human body odour than uninfected insects, a study suggests.
While it is advisable to be wary of malaria, experts agree that it is unlikely that the region is on the verge of an outbreak.
Mosquitoes are deadly efficient disease transmitters. Research conducted at Michigan State University, however, demonstrates that they also can be equally adept in curing diseases such as malaria.
Substantial stocks of the insecticide DDT on the ocean floor off Los Angeles have all but vanished.
In January, the European Commission advised the EU not to use neonicotinoids, a relatively new class of agricultural insecticides.
Disabling a unique signalling protein puts the brakes on the life cycle of the malaria parasite, a new study reports.
It may be tempting to think that higher temperatures will lead to more mosquitoes and therefore to more malaria...
Substandard and falsified drugs are readily available in the private marketplace and probably contribute to anti-tuberculosis drug resistance in low- and middle-income countries. This issue warrants further investigation through large-scale studies of drug quality in all markets.
Threatened reductions in foreign aid from the European Union and its struggling governments could undermine efforts to combat malaria, international health experts say.
On this episode of Eye to Eye, I had the opportunity to interview Richard Tren, a leading proponent for the use of DDT in the fight against the deadly disease malaria.
Malaria remains one of the leading killer diseases in the world, and the infection rate in Africa especially sub-Saharan Africa remains the highest in the world.
Scientists say new research into Malaria will help provide new ways to combat the deadly disease.
A new research has identified resistance to artemisinin in new strains of Plasmodium falciparum--the parasite that causes malaria.
Over-diagnosis of malaria by microscopy in the Kilombero Valley, Southern Tanzania: an evaluation of the utility and cost-effectiveness of rapid diagnostic tests
Early and accurate diagnosis of febrile patients is essential to treat uncomplicated malaria cases properly, prevent severe malaria, and avert unnecessary anti-malarial treatments.
Vector-control personnel's knowledge, perceptions and practices towards insecticides used for indoor residual spraying in Limpopo Province, South Africa
Contradictory arguments regarding the benefits and harm of insecticides, especially DDT, have caused concerns in different societal circles, threatening to undermine the achievements of the indoor residual spraying (IRS) programme in South Africa.
Treatment of fevers prior to introducing rapid diagnostic tests for malaria in registered drug shops in Uganda
Since drug shops play an important role in treatment of fever, introducing rapid diagnostic tests (RDTs) for malaria at drug shops may have the potential of targeting anti-malarial drugs to those with malaria parasites and improve rational drug use
Verification of clinically diagnosed cases during malaria elimination programme in Guizhou Province of China
China is implementing a National Malaria Elimination Programme.
Challenges for malaria elimination in Zanzibar: pyrethroid resistance in malaria vectors and poor performance of long-lasting insecticide nets
The sustainability of the gains achieved in malaria control in Zanzibar is seriously threatened by the resistance of malaria vectors to pyrethroids and the short-lived efficacy of LLINs.Read more »