A randomized, double-blinded, placebo-controlled study was conducted to examine the effect of spatial repellent (SR) in households at risk of malaria in Indonesia. Following presumptive radical cure for malaria in 180 adult men representing sentinels of new infection in four clusters within two villages, all households were given either metofluthrin or placebo mosquito coils. Weekly blood smear screening and human-landing mosquito catches were done throughout the 6 months intervention. Malaria infections occurred in 61 subjects living in placebo households and 31 subjects living in SR coil households, suggesting a 52% protective effect of SR. Likewise, anopheles indoor human landing rates were 32% lower in homes receiving SR coils. Differences in the malaria attack rate between SR- and placebo-treated homes was significant when not accounting for the effects of clustering. When the analysis was adjusted for intra-cluster correlation, the differences between SR- and placebo-treated homes were not statistically significant. The findings provide evidence of SR public health benefit and support a larger trial statistically powered to detect those effects. more »
Travellers are being urged to take precaution during the holiday season to guard themselves against malaria. South Africa has recorded a rise in malaria-related deaths, warned the National Institute for Communicable Diseases.
Scientists have developed a tool for coding DNA that will help to monitor drug-resistant strains.
What happens to lost nets: a multi-country analysis of reasons for LLIN attrition using 14 household surveys in four countries
While significant focus has been given to net distribution, little is known about what is done with nets that leave a household, either to be used by others or when they are discarded.
Apparently we no longer live in a world that values technological advancement.
The World Health Organization (WHO) has declared, "A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century".
Last year, Prof Henk Bouwman of North-West University and co-authors published a paper in a respectable journal, Environmental Research, claiming that DDT spraying led to thinning of bird eggshells.
The environmental science journal Environmental Research has published an article by nine malaria experts exposing major errors in a research paper on DDT and bird eggshells.
In Southern Africa, the malaria season typically begins with the summer rains in November and ends in April. In this region, the co-ordination of malaria control efforts between neighbouring states has dramatically reduced the incidence of malaria.Read more »
Scientists have released details of a raft of new chemicals with potent anti-malarial properties which could open the way to new drugs to fight the disease.
Liberia is struggling to cope with malaria patients in the wake of the deadly epidemic
Case Western Reserve University malaria expert Brian Grimberg was named to Foreign Policy's 100 Leading Global Thinkers for 2014, the publication announced today.
Monkey malaria, which is three times more severe than other forms of malaria, now accounts for two-thirds of human malaria cases in Malaysian Borneo
Asia-Pacific leaders have agreed to eradicate malaria by 2030, a decision likely to avert millions of deaths given the increasing drug resistance of the mosquito-borne disease in Southeast AsiaRead more »
Insecticide-treated net use before and after mass distribution in a fishing community along Lake Victoria, Kenya: successes and unavoidable pitfalls
The effectiveness of mass distribution of ITNs, requires careful analysis of successes and failures if impacts are to be sustained over the long term.
To investigate the genomic basis of vectorial capacity and explore new avenues for vector control, we sequenced the genomes of 16 anopheline mosquito species from diverse locations spanning ~100 million years of evolution.
Installation of insecticide-treated durable wall lining: evaluation of attachment materials and product durability under field conditions.
Based on a series of systematic stress tests, optimized fixing products for polyethylene insecticide treated durable wall lining (DL) attachments were identified.
First report of an exophilic Anopheles arabiensis population in Bissau city, Guinea-Bissau: recent introduction or sampling bias?
Results point to the presence of a previously undetected outdoor population of An. arabiensis in Antula, which appears to have expanded recently, highlighting the importance of complementing indoor-based mosquito collections with sampling methods targeting outdoor adults and immature stages for a more complete assessment of mosquito biodiversity.
Primaquine is the only generally available anti-malarial that prevents relapse in vivax and ovale malaria, and the only potent gametocytocide in falciparum malaria.Read more »