Malaria with total resistance to the antimalarial drug artemisinin has taken hold in Burma and spread close to the border with India, threatening to render crucial medicines useless, scientists have warned. If the resistant parasite reached India it would pose a serious threat to the chances of global control and eradication of the killer mosquito-borne disease, said Charles Woodrow of the Mahidol-Oxford tropical medicine research unit. And if resistance spread from Asia to Africa, or emerges in Africa independently - as has been seen before with previously effective but now powerless antimalarials - "millions of lives will be at risk", they said in a report.
"[Burma] is considered the front line in the battle against artemisinin resistance as it forms a gateway for resistance to spread to the rest of the world," said Woodrow, who led the Oxford study. In a study published in the Lancet Infectious Diseases journal, Woodrow's team collected 940 parasite samples at 55 malaria treatment centres across Burma and its border regions. more »
Human stem cells engineered to produce renewable sources of mature, liver-like cells can be grown and infected with malaria to test potentially life-saving drugs, new research from the Massachusetts Institute of Technology has shown.
An ambitious goal - to eliminate malaria from the Asia-Pacific region by 2030 - faces formidable hurdles but is achievable if enough political will and funding are available to fight the mosquito-borne disease, health experts say.
Disease has been resilient, speakers say, and efforts to eradicate it require a local focus
Apparently we no longer live in a world that values technological advancement.
The World Health Organization (WHO) has declared, "A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century".
Last year, Prof Henk Bouwman of North-West University and co-authors published a paper in a respectable journal, Environmental Research, claiming that DDT spraying led to thinning of bird eggshells.
The environmental science journal Environmental Research has published an article by nine malaria experts exposing major errors in a research paper on DDT and bird eggshells.
In Southern Africa, the malaria season typically begins with the summer rains in November and ends in April. In this region, the co-ordination of malaria control efforts between neighbouring states has dramatically reduced the incidence of malaria.Read more »
The ancestors of a large family of parasites--including those that cause malaria--were equipped to become parasites much earlier in their lineage than previously assumed, according to University of British Columbia (UBC) research.
Thanks to a novel approach developed by scientists at Albert Einstein College of Medicine of Yeshiva University and described in the January 20 online edition of ACS Chemical Biology, researchers can readily screen thousands of drugs to find those potentially able to kill P. falciparum.
It seems like a no-brainer: Distribute insecticide-treated nets to poor countries most at risk from malaria and we can reduce the death toll of this major global killer.
Despite a sharp drop in malaria-related deaths over the past decade, a veteran doctor here, in the heart of the world's malaria belt, says now is the time to wage a large-scale battle with the mosquito-borne disease.
The Gambia government has been conferred with the 2015 African Leaders Malaria Alliance Award (ALMA), for its excellence effort in the implementation of vector control in the country.Read more »
Determinants of malaria diagnostic uptake in the retail sector: qualitative analysis from focus groups in Uganda
In order to boost demand for RDTs, this research suggests that private sector RDTs will have to be made convenient and affordable and that targeted behaviour change campaigns should strive to increase the perceived value of diagnosis.
Malaria parasite carriage and risk determinants in a rural population: a malariometric survey in Rwanda
Efforts to further reduce transmission and eventually eliminate malaria locally should focus on investments in programmes that improve house structure features (that limit indoor malaria transmission), making insecticide-treated bed nets and indoor residual spraying implementation more effective.
Insecticide-treated net use before and after mass distribution in a fishing community along Lake Victoria, Kenya: successes and unavoidable pitfalls
The effectiveness of mass distribution of ITNs, requires careful analysis of successes and failures if impacts are to be sustained over the long term.
To investigate the genomic basis of vectorial capacity and explore new avenues for vector control, we sequenced the genomes of 16 anopheline mosquito species from diverse locations spanning ~100 million years of evolution.
What happens to lost nets: a multi-country analysis of reasons for LLIN attrition using 14 household surveys in four countries
While significant focus has been given to net distribution, little is known about what is done with nets that leave a household, either to be used by others or when they are discarded.Read more »