Research

Do we still need a malaria vaccine?

B. Greenwood & G. Targett | 27 Aug 2023 | Parasite Immunology

An unexpectedly large reduction in the burden of malaria has recently been achieved in a number of malaria endemic countries following the scaling up of effective treatment and simple vector control programmes.

Government-Controlled Research & Development - A Recipe for Disaster

Roger Bate & Richard Tren | 22 May 2023 | American Enterprise Institute

This paper warns against the proposed May 2006 World Health Assembly treaty to increase state control of research and development into new drugs.

Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial

Pedro L. Alonso et al | 16 Oct 2023 | The Lancet

Development of an effective malaria vaccine could greatly contribute to disease control. RTS,S/AS02A is a pre-erythrocytic vaccine candidate based on Plasmodium falciparum circumsporozoite surface antigen. We aimed to assess vaccine efficacy, immunogenicity, and safety in young African children.