Mwinyi Msellem et al | 28 Apr 2009 | PloS Medicine
The use of rapid diagnostic tests (RDTs) for Plasmodium falciparum malaria is being suggested to improve diagnostic efficiency in peripheral health care settings in Africa.
Roger Bate, Richard Tren, Kimberly Hess, Lorraine Mooney & Karen Porter | 27 Apr 2009 | African Journal of Pharmacy and Pharmacology
Researchers procured a range of antimalarial, antibiotic and antimycobacterial drugs from cities in six countries: Ghana, India, Kenya, Nigeria, Tanzania, and Uganda. Semi-quantitative thin-layer chromatography (TLC) and disintegration tests, Raman spectrometry, and near-infrared (NIR) spectrometry were used to measure the concentration of active ingredients and excipients (spectrometry only) to determine whether the tested samples were of good quality.
None | 21 Apr 2009 | Africa Fighting Malaria
Roll Back Malaria's theme for World Malaria Day 2009 is "Counting Malaria Out". AFM supports the Roll Back Malaria Partnership in their efforts to improve data collection and track progress of malaria control efforts. For the past year, AFM and its partners have focused on "counting out" poor-quality antimalarial drugs.
Joan Nankabirwa et al | 16 Apr 2009 | Malaria Journal
In Uganda, like in many other countries traditionally viewed as harbouring very high malaria transmission, the norm has been to recommend that febrile episodes are diagnosed as malaria. In this study, the policy implications of such recommendations are revisited.
Sarah G Staedke et al | 14 Apr 2009 | The Lancet
Home management of malaria—the presumptive treatment of febrile children with antimalarial drugs—is advocated to ensure prompt effective treatment of the disease. We assessed the effect of home delivery of artemether-lumefantrine on the incidence of antimalarial treatment and on clinical outcomes in children from an urban setting with fairly low malaria transmission.
Lucy A. Smith et al | 16 Mar 2009 | American Journal of Tropical Medicine and Hygiene
Effective case management of uncomplicated malaria is a cornerstone of successful malaria control. With current calls for the global elimination of malaria, all strategies to control malaria need to reach the highest achievable level of effective implementation.
Sodiomon B Sirima et al | 16 Mar 2009 | Malaria Journal
Artesunate (AS) plus amodiaquine (AQ) is one artemisinin-based combination (ACT) recommended by the WHO for treating Plasmodium falciparum malaria. Fixed-dose AS/AQ is new, but its safety and efficacy are hitherto untested.
Roger Bate, Richard Tren, Kimberly Hess & Amir Attaran | 25 Feb 2009 | Malaria Journal
New artemisinin combination therapies pose difficulties of
implementation in developing and tropical settings because they have a
short shelf-life (two years) relative to the medicines they replace.
This limits the reliability and cost of treatment, and the
acceptability of this treatment to health care workers. A multi-pronged
investigation was made into the chemical and physical stability of
fixed dose combination artemether-lumefantrine (FDC-ALU) stored under
heterogeneous, uncontrolled African conditions, to probe if a
shelf-life extension might be possible.
Bamgboye M. Afolabi et al | 19 Feb 2009 | Malaria Journal
This study found that despite the fact that treated nets were distributed widely across Nigeria, the use of this commodity was still very low in the Sahel Savanna region. Future campaigns should include more purposeful social and health education on the importance and advantages of the use of treated nets to save lives in the Sahel Savannah region of Nigeria.
William Rogers et al | 12 Jan 2009 | Malaria Journal
Resistance to anti-malarial drugs hampers control efforts and increases the risk of morbidity and mortality from malaria. The efficacy of standard therapies for uncomplicated Plasmodium falciparum and Plasmodium vivax malaria was assessed in Chumkiri, Kampot Province, Cambodia.