Research

Combining Indoor Residual Spraying and Insecticide-Treated Net Interventions

Immo Kleinschmidt et al | 29 Sep 2009 | American Journal of Tropical Medicine and Hygiene

Does scaling up of malaria control by combining indoor residual spraying (IRS) and long-lasting insecticidal nets (LLIN) enhance protection to populations?

Do we still need a malaria vaccine?

B. Greenwood & G. Targett | 27 Aug 2009 | Parasite Immunology

An unexpectedly large reduction in the burden of malaria has recently been achieved in a number of malaria endemic countries following the scaling up of effective treatment and simple vector control programmes.

Efficacy of artesunate-amodiaquine for treating uncomplicated P. falciparum malaria in Sub-Saharan Africa: a multi-centre analysis

Julien Zwang et al | 23 Aug 2009 | Malaria Journal

Artesunate and amodiaquine (AS&AQ) is at present the world's second most widely used artemisinin-based combination therapies (ACT). Evaluating the efficacy of ACT recently adopted by the World Health Organisation (WHO) and deployed over 80 countries was necessary to make evidence base drug policy.

Drug Use in Nigeria

None | 29 Jul 2009 | Africa Fighting Malaria

For decades, Nigeria has been plagued by counterfeit and poor-quality medicines, yet little information exists on the extent to which healthcare personnel are aware of counterfeit and substandard medicines, and how this influences their behavior.

Decreased motivation in the use of insecticide-treated nets in a malaria endemic area in Burkina Faso

Lea Pare Toe et al | 29 Jul 2009 | Malaria Journal

The use of insecticide-treated nets (ITNs) is an important tool in the Roll Back Malaria strategy. For ITNs to be effective they need to be used correctly. Previous studies have shown that many factors, such as wealth, access to health care, education, ethnicity and gender, determine the ownership and use of ITNs.

Focusing on Quality Patient Care in the New Global Subsidy for Malaria Medicines

Suerie Moon et al | 21 Jul 2009 | PloS Medicine

Almost 40 years ago, Chinese scientists rediscovered the near-miraculous potency of artemisinin derivatives against malaria. Today, we are approaching a decade since the WHO recommended that ACTs replace older antimalarials rendered ineffective by resistance.

Fever treatment in the absence of malaria transmission in an urban informal settlement in Nairobi, Kenya

Yazoume Ye et al | 15 Jul 2009 | Malaria Journal

In sub-Saharan Africa, knowledge of malaria transmission across rapidly proliferating urban centres and recommendations for its prevention or management remain poorly defined.

Pilot Study of Essential Drug Quality in Two Major Cities in India

Roger Bate et al | 23 Jun 2009 | PLoS One

A pilot study was conducted in two major cities in India, Delhi and Chennai, to explore the question/hypothesis/extent of substandard and counterfeit drugs available in the market and to discuss how the Indian state and federal governments could improve drug regulation and more importantly regulatory enforcement to combat these drugs.

Use of drugs, perceived drug efficacy and preferred providers for febrile children: implications for home management of fever

Elizeus Rutebemberwa et al | 12 Jun 2009 | Malaria Journal

Community distribution of anti-malarials and antibiotics has been recommended as a strategy to reduce the under-five mortality due to febrile illnesses in sub-Saharan Africa. However, drugs distributed in these interventions have been considered weak by some caretakers and utilization of community medicine distributors has been low.

Marked Increase in Child Survival after Four Years of Intensive Malaria Control

Immo Kleinschmidt et al | 03 Jun 2009 | American Journal of Tropical Medicine and Hygiene

In malaria-endemic countries in Africa, a large proportion of child deaths are directly or indirectly attributable to infection with Plasmodium falciparum. Four years after high coverage, multiple malaria control interventions were introduced on Bioko Island, Equatorial Guinea, changes in infection with malarial parasites, anemia, and fever history in children were estimated and assessed in relation to changes in all-cause under-5 mortality.