Research

SMS for Life: a pilot project to improve anti-malarial drug supply management in rural Tanzania using standard technology

Jim Barrington et al | 27 Oct 2010 | Malaria Journal

The SMS for Life pilot provided visibility of anti-malarial stock levels to support more efficient stock management using simple and widely available SMS technology, via a public-private partnership model that worked highly effectively.

Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial

Frank Smithuis et al | 09 Sep 2010 | The Lancet Infectious Diseases

Artemisinin-combination therapy (ACT) is recommended as first-line treatment of falciparum malaria throughout the world, and fixed-dose combinations are preferred by WHO; whether a single gametocytocidal dose of primaquine should be added is unknown.

Antimalarial medicine diversion: stock-outs and other public health problems

Roger Bate, Kimberly Hess & Lorraine Mooney | 02 Sep 2010 | Research and Reports in Tropical Medicine

Antimalarial medicine diversion has been seen across numerous African markets and can lead to serious stock-outs in the public sector, which can be dangerous to countries with high burdens of disease. This study discusses the numbers of diverted antimalarial medicines from several samplings in Africa.

Assessing Website Pharmacy Drug Quality: Safer Than You Think?

Roger Bate & Kimberly Hess | 13 Aug 2010 | PLoS One

Internet-sourced drugs are often considered suspect. The WHO reports that drugs from websites that conceal their physical address are counterfeit in over 50 percent of cases; the FDA works with the NABP to regularly update a list of websites likely to sell drugs that are illegal or of questionable quality.

Who Gets Prompt Access to Artemisinin-Based Combination Therapy? A Prospective Community-Based Study in Children from Rural Kilosa, Tanzania

Daudi Simba et al | 10 Aug 2010 | PLoS One

Prompt access to ACT among febrile children was unacceptably low, due mainly to limited availability of subsidised ACT at the location where most caretakers sought care. There is urgent need to accelerate implementation of strategies that will ensure availability of ACT at an affordable price in remote rural areas, where the burden of malaria is highest.

Patent Medicine Sellers: How Can They Help Control Childhood Malaria?

Rosamund Akuse et al | 19 Jul 2010 | Malaria Research and Treatment

Roll Back Malaria Initiative encourages participation of private health providers in malaria control because mothers seek care for sick children from them. This study investigated Patent Medicine Sellers (PMS) management of presumptive malaria in children in order to identify how they can assist malaria control.

Use of RDTs to improve malaria diagnosis and fever case management at primary health care facilities in Uganda

Daniel Kyabayinze et al | 12 Jul 2010 | Malaria Journal

Early and accurate diagnosis of malaria followed by prompt treatment reduces the risk of severe disease in malaria endemic regions.

A pharmacy too far? Equity and spatial distribution of outcomes in the delivery of subsidized ACTs through private drug shops

Justin M Cohen et al | 02 Jul 2010 | BMC Health Services Research

Millions of individuals with malaria-like fevers purchase drugs from private retailers, but ACTs, the only effective treatment in regions with high levels of resistance to older drugs, are rarely obtained through these outlets due to their relatively high cost.

Anti-malarial drug quality in Lagos and Accra - a comparison of various quality assessments

Roger Bate & Kimberly Hess | 11 Jun 2010 | Malaria Journal

Two major cities in West Africa, Accra, the capital of Ghana, and Lagos, the largest city of Nigeria, have significant problems with substandard pharmaceuticals. Both have actively combated the problem in recent years, particularly by screening products on the market using the Global Pharma Health Fund e.V. Minilab protocol.

A situational analysis of pharmacovigilance plans in the Global Fund Malaria and U.S. President's Malaria Initiative proposals

Andy Stergachis et al | 30 May 2010 | Malaria Journal

There were relatively few requests for funding for pharmacovigilance activities, demonstrating a lack of emphasis placed on pharmacovigilance systems in recipient countries.