Research

Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common

Nicholas J White et al | 14 Dec 2012 | Malaria Journal

In areas of low malaria transmission, it is currently recommended that a single dose of primaquine (0.75 mg base/kg; 45 mg adult dose) be added to artemisinin combination treatment (ACT) in acute falciparum malaria to block malaria transmission.

The role of pre-shipment batch testing in ensuring good medicine quality

Roger Bate & Kimberly Hess | 05 Dec 2012 | MalariaWorld Journal

Most donor agencies only procure drugs approved by a Stringent Regulatory Authority or the World Health Organization (WHO) Prequalification Programme in an effort to ensure high quality. However...

New Test Could Revolutionize Malaria Treatment

Matthew Hilburn | 29 Nov 2012 | Voice of America

A new diagnostic test could revolutionize the treatment of malaria, one of the world's most persistent and deadly diseases, making it possible to diagnose the illness from a single drop of blood or saliva.

Private Sector Drug Shops in Integrated Community Case Management of Malaria, Pneumonia, and Diarrhea in Children in Uganda

Phyllis Awor et al | 19 Nov 2012 | American Journal of Tropical Medicine and Hygiene

We conducted a survey involving 1,604 households to determine community care-seeking patterns and 163 exit interviews to determine appropriateness of treatment of common childhood illnesses at private sector drug shops in two rural districts of Uganda.

Travel and fake artesunate: a risky business

Carlos J Chaccour et al | 22 Sep 2012 | The Lancet

In October, 2011, a previously well 28-year-old woman from Spain was admitted to our hospital with a 5 day history of fever, rigors, headache, back pain, and myalgia.

Trends in availability and prices of subsidized ACT over the first year of the AMFm: evidence from remote regions of Tanzania

Prashant Yadav et al | 28 Aug 2012 | Malaria Journal

The AMFm led to large increases in availability of low priced ACT in Tanzania, with no significant variation in availability based on remoteness. Availability did remain lower and prices remained higher in Rukwa, which is a more remote region overall.

Reductions in Artemisinin-Based Combination Therapy Consumption after the Nationwide Scale up of Routine Malaria Rapid Diagnostic Testing in Zambia

Joshua Yukich et al | 13 Aug 2012 | American Journal of Tropical Medicine and Hygiene

Rapid diagnostic tests may contribute to rationalization of treatment of febrile illness and reduce antimalarial drug consumption in Africa; however, their impact may be greater in lower transmission areas. National scale data will be necessary to confirm these findings.

Factors associated with utilization of community health workers in improving access to malaria treatment among children in Kenya

James Kisia et al | 30 Jul 2012 | Malaria Journal

The potential for utilization of CHWs in improving access to malaria treatment at the community level is promising.

Subsidizing artemisinin-based combination therapies: a preliminary investigation of the Affordable Medicines Facility - malaria

Roger Bate et al | 18 Jul 2012 | Research and Reports in Tropical Medicine

The AMFm is at best imperfectly displacing undesirable monotherapies, some portion of which are replaced by ACTs lacking sufficient API, which are often sold at prices exceeding government authorization.

Anti-infective medicine quality: analysis of basic product quality by approval status and country of manufacture

Roger Bate et al | 16 Jul 2012 | Research and Reports in Tropical Medicine

The results strongly indicate that approval by either an SRA or the WHO is correlated with higher medicine quality at a statistically significant level. The comparatively high failure rates among WHO-approved products suggest there may be some weakness in post-marketing surveillance of these products, especially of Chinese-made WHO-approved products.